Inhibitory properties of camel whey protein hydrolysates toward liver cancer cells, dipeptidyl peptidase-IV, and inflammation

Dipeptidyl Peptidase-IV Inhibitory Activity of Peptides in Porcine Skin Gelatin Hydrolysates

Targeting Dipeptidyl Peptidase IV (CD26)

Dipeptidyl peptidase IV in human lymphocytes: molecular properties.

Dipcptidyl peptidase IV (DPP IV; EC 3.4.14.5). an cctocnzyme o n the cell membrane of T-lymphocytes, has bccn shown t o play an important role in the regulation of lymphocyte proliferation and activation. Evidence for this has been provided by the use of specific inhibitors, which revealed (a) a supprcssion of the proliferation of peripheral blood lymphocytes by mitogenic lectins 111, and (b) a...

The role of CD26/dipeptidyl peptidase IV in cancer.

CD26/DPPIV is a multifunctional cell surface protein that is widely expressed in most cell types including T lymphocytes, on which it is a marker of activation. It is also present in serum and other body fluids in a truncated form (sCD26/DPPIV). It preferentially cleaves N-terminal dipeptides from polypeptides with proline or alanine in the penultimate position, and in doing so, regulates the a...

Dipeptidyl peptidase IV and its implication in cancer

Dipeptidyl peptidase IV (DPP-IV, EC 3.4.14.5), also known as CD26, is a serine aminopeptidase that preferentially cleaves Xaa-Pro or Xaa-Ala dipeptides from the N-terminus of oligopeptides and processes regulatory peptides in vivo, leading to their biological activation or inactivation. The ezyme is a homodimer and each subunit is formed by a ab-hydrolase domain and a b-propeller domain, involv...